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Klotho in Clinical Nephrology

Diagnostic and Therapeutic Implications

Javier A. Neyra, Ming Chang Hu and Orson W. Moe
CJASN January 2021, 16 (1) 162-176; DOI: https://doi.org/10.2215/CJN.02840320
Javier A. Neyra
1Charles and Jane Pak Center for Mineral Metabolism and Clinical Research, Dallas, Texas
2Department of Internal Medicine, University of Texas Southwestern Medical Center, Dallas, Texas
3Division of Nephrology, Bone and Mineral Metabolism, Department of Internal Medicine, University of Kentucky, Lexington, Kentucky
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Ming Chang Hu
1Charles and Jane Pak Center for Mineral Metabolism and Clinical Research, Dallas, Texas
2Department of Internal Medicine, University of Texas Southwestern Medical Center, Dallas, Texas
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Orson W. Moe
1Charles and Jane Pak Center for Mineral Metabolism and Clinical Research, Dallas, Texas
2Department of Internal Medicine, University of Texas Southwestern Medical Center, Dallas, Texas
4Department of Physiology, University of Texas Southwestern Medical Center, Dallas, Texas
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Clinical Journal of the American Society of Nephrology: 16 (1)
Clinical Journal of the American Society of Nephrology
Vol. 16, Issue 1
January 07, 2021
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Klotho in Clinical Nephrology
Javier A. Neyra, Ming Chang Hu, Orson W. Moe
CJASN Jan 2021, 16 (1) 162-176; DOI: 10.2215/CJN.02840320

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Klotho in Clinical Nephrology
Javier A. Neyra, Ming Chang Hu, Orson W. Moe
CJASN Jan 2021, 16 (1) 162-176; DOI: 10.2215/CJN.02840320
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  • Article
    • Abstract
    • Introduction
    • Physiology of Klotho
    • Klotho in Disease States
    • Potential Mechanisms of Klotho-Mediated Kidney and Cardiovascular Protection
    • Biomarker Candidacy in Human Kidney Disease
    • Measurement of Soluble Klotho in Humans
    • Klotho-Focused Therapies
    • Summary and Call for Action
    • Disclosures
    • Funding
    • Footnotes
    • References
  • Figures & Data Supps
  • Info & Metrics
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More in this TOC Section

  • Decision Algorithm for Prescribing SGLT2 Inhibitors and GLP-1 Receptor Agonists for Diabetic Kidney Disease
  • Cuffless Blood Pressure Monitoring
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Keywords

  • Klotho;
  • nephrology;
  • kidney;
  • diagnosis;
  • therapy

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