CJASN
HOME HELP FEEDBACK SUBSCRIPTIONS ARCHIVE SEARCH
QUICK SEARCH:   [advanced]


     

Published ahead of print on February 6, 2008
Clinical Journal of the American Society of Nephrology
© 2008 American Society of Nephrology
doi: 10.2215/CJN.05021107
This Article
Right arrow Full Text (Rapid PDF)
Right arrow All Versions of this Article:
CJN.05021107v1
3/2/471    most recent
Right arrow Alert me when this article is cited
Right arrow Alert me if a correction is posted
Services
Right arrow Email this article to a friend
Right arrow Similar articles in this journal
Right arrow Similar articles in PubMed
Right arrow Alert me to new issues of the journal
Right arrow Download to citation manager
Right arrow reprints & permissions
Citing Articles
Right arrow Citing Articles via HighWire
Right arrow Citing Articles via Google Scholar
Google Scholar
Right arrow Articles by Abecassis, M.
Right arrow Articles by Gaston, R. S.
Right arrow Search for Related Content
PubMed
Right arrow PubMed Citation
Right arrow Articles by Abecassis, M.
Right arrow Articles by Gaston, R. S.

Received November 15, 2007
Accepted on December 10, 2007

ORIGINAL ARTICLES

Kidney Transplantation as Primary Therapy for End-Stage Renal Disease: A National Kidney Foundation/Kidney Disease Outcomes Quality Initiative (NKF/KDOQITM) Conference

Michael Abecassis , Stephen T. Bartlett , Allan J. Collins , Connie L. Davis , Francis L. Delmonico , John J. Friedewald , Rebecca Hays , Andrew Howard , Edward Jones , Alan B. Leichtman , Robert M. Merion , Robert A. Metzger , Francoise Pradel , Eugene J. Schweitzer , Ruben L. Velez , and Robert S. Gaston 1

Division of Nephrology, University of Alabama at Birmingham, Birmingham, Alabama


1 To whom correspondence should be addressed. E-mail: rgaston{at}uab.edu.


  Abstract

Background and objectives: Kidney transplantation is the most desired and cost-effective modality of renal replacement therapy for patients with irreversible chronic kidney failure (end-stage renal disease, stage 5 chronic kidney disease). Despite emerging evidence that the best outcomes accrue to patients who receive a transplant early in the course of renal replacement therapy, only 2.5% of incident patients with end-stage renal disease undergo transplantation as their initial modality of treatment, a figure largely unchanged for at least a decade.

Design, setting, participants, & measurements: The National Kidney Foundation convened a Kidney Disease Outcomes Quality Initiative (KDOQI) conference in Washington, DC, March 19 through 20, 2007, to examine the issue. Fifty-two participants representing transplant centers, dialysis providers, and payers were divided into three work groups to address the impact of early transplantation on the chronic kidney disease paradigm, educational needs of patients and professionals, and finances of renal replacement therapy.

Results: Participants explored the benefits of early transplantation on costs and outcomes, identified current barriers (at multiple levels) that impede access to early transplantation, and recommended specific interventions to overcome those barriers.

Conclusions: With implementation of early education, referral to a transplant center coincident with creation of vascular access, timely transplant evaluation, and identification of potential living donors, early transplantation can be an option for substantially more patients with chronic kidney disease.


This article has been cited by other articles:


Home page
 Clin EthicsHome page
R. Elias
Confidentiality and consent in living kidney transplantation: is it essential for a donor to know that their recipient has HIV disease?
Clin Ethics, December 1, 2009; 4(4): 202 - 207.
[Abstract] [Full Text] [PDF]

Home page
 CJASNHome page
R. S. Gaston
Must Health Literacy Be a Prerequisite for Kidney Transplantation?
Clin. J. Am. Soc. Nephrol., January 1, 2009; 4(1): 16 - 17.
[Full Text] [PDF]


HOME HELP FEEDBACK SUBSCRIPTIONS ARCHIVE SEARCH
Copyright © 2008 by the American Society of Nephrology.