CJASN
HOME HELP FEEDBACK SUBSCRIPTIONS ARCHIVE SEARCH TABLE OF CONTENTS
QUICK SEARCH:   [advanced]


     

Published ahead of print on November 14, 2007
Clin J Am Soc Nephrol 3: 281-287, 2008
© 2008 American Society of Nephrology
doi: 10.2215/CJN.02590607
This Article
Right arrow Full Text
Right arrow Full Text (PDF)
Right arrow All Versions of this Article:
CJN.02590607v1
3/1/281    most recent
Right arrow Alert me when this article is cited
Right arrow Alert me if a correction is posted
Right arrow Citation Map
Services
Right arrow Email this article to a friend
Right arrow Similar articles in this journal
Right arrow Similar articles in PubMed
Right arrow Alert me to new issues of the journal
Right arrow Download to citation manager
Right arrow reprints & permissions
Citing Articles
Right arrow Citing Articles via HighWire
Right arrow Citing Articles via Google Scholar
Google Scholar
Right arrow Articles by Fishbane, S.
Right arrow Search for Related Content
PubMed
Right arrow PubMed Citation
Right arrow Articles by Fishbane, S.

Moving Points in Nephrology

N-Acetylcysteine in the Prevention of Contrast-Induced Nephropathy

Steven Fishbane

Winthrop-University Hospital, Mineola, New York, and State University of New York School of Medicine, Stony Brook, New York

Correspondence: Dr. Steven Fishbane, 200 Old Country Road, #135, Mineola, NY 11501. Phone: 516-663-2169; Fax: 516-663-2179; E-mail: sfishbane{at}winthrop.org

Background and objectives: Contrast-induced nephropathy (CIN) is a common clinical problem that is growing in importance as an increasing number of tests and procedures that utilize contrast media are performed.

Design, setting, participants, and measurements: The biological and pharmacological properties of n-acetylcysteine (NAC) are reviewed, as well as the current literature relevant to the ability of NAC to prevent CIN.

Results: After publication of a seminal study by Tepel et al. in 2000, there has been a surge in interest regarding the ability of NAC to reduce the risk for CIN. Since then a large number of studies, mostly with relatively small sample sizes, have been published.

Conclusions: The results have been remarkably varied with some studies finding great efficacy with NAC but most finding no significant benefit.




This article has been cited by other articles:


Home page
 Antimicrob. Agents Chemother.Home page
Z. Odabasi, A. Karaalp, H. Cermik, J. Mohr, E. T. Tigen, M. Koc, and V. Korten
Reduction of Amphotericin B-Induced Renal Tubular Apoptosis by N-Acetylcysteine
Antimicrob. Agents Chemother., July 1, 2009; 53(7): 3100 - 3102.
[Abstract] [Full Text] [PDF]

Home page
 RadiologyHome page
M. Sendeski, A. Patzak, T. L. Pallone, C. Cao, A. E. Persson, and P. B. Persson
Iodixanol, Constriction of Medullary Descending Vasa Recta, and Risk for Contrast Medium-induced Nephropathy
Radiology, June 1, 2009; 251(3): 697 - 704.
[Abstract] [Full Text] [PDF]

Home page
 NDT PlusHome page
N. Lameire, W. van Biesen, E. Hoste, and R. Vanholder
The prevention of acute kidney injury an in-depth narrative review: Part 2: Drugs in the prevention of acute kidney injury
NDT Plus, February 1, 2009; 2(1): 1 - 10.
[Abstract] [Full Text] [PDF]

Home page
 Mayo Clin Proc.Home page
S. Goldfarb, P. A. McCullough, J. McDermott, and S. B. Gay
Contrast-Induced Acute Kidney Injury: Specialty-Specific Protocols for Interventional Radiology, Diagnostic Computed Tomography Radiology, and Interventional Cardiology
Mayo Clin. Proc., February 1, 2009; 84(2): 170 - 179.
[Abstract] [Full Text] [PDF]


HOME HELP FEEDBACK SUBSCRIPTIONS ARCHIVE SEARCH TABLE OF CONTENTS
Copyright © 2008 by the American Society of Nephrology.