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Department of Medicine, Hospital of Saint Raphael and Department of Internal Medicine, Yale University School of Medicine, New Haven, Connecticut
Correspondence: Dr. Alan S. Kliger, Department of Medicine, Hospital of Saint Raphael, 1450 Chapel Street, New Haven, CT 06511. Phone: 203-789-3203; Fax: 203-789-3222; E-mail: akliger{at}srhs.org
Clinical outcomes have not improved substantially for patients treated with conventional thrice weekly hemodialysis. More intensive hemodialysis regimens, including daily short dialysis, and nocturnal prolonged dialysis show promise to improve morbidity and mortality. Published studies and trials underway examining these therapies are reviewed.
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