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Published ahead of print on July 9, 2009
Clin J Am Soc Nephrol 4: 1388-1400, 2009
© 2009 American Society of Nephrology
doi: 10.2215/CJN.01590309

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In-Depth Review

Staphylococcus aureus Infections in Hemodialysis: What a Nephrologist Should Know

Stefaan J. Vandecasteele, Johan R. Boelaert, and An S. De Vriese

Department of Nephrology and Infectious Diseases, AZ Sint-Jan Brugge-Oostende AV, Brugge, Belgium

Correspondence: Dr. Stefaan J. Vandecasteele, Department of Nephrology and Infectious Diseases, AZ Sint-Jan Brugge-Oostende AV, Ruddershove 10, Brugge, Belgium. Phone: ++32-50-45-22-00; Fax: ++32-50-45-22-99; E-mail: stefaan.vandecasteele{at}azbrugge.be

Staphylococcus aureus is a formidable pathogen that has the ability to colonize approximately half the dialysis population without any sign of disease but is also capable of causing wound and tissue infections; fulminant septicemia; and chronic, difficult-to-eradicate and often foreign body-related infections. S. aureus is the main cause of infectious morbidity and mortality in hemodialysis patients. This review highlights the importance of S. aureus infections in daily hemodialysis practice from a clinical viewpoint, starting from some key issues in the pathogenesis of staphylococcal infections.







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