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Pregnancy after Kidney Transplantation

Dianne B. McKay^*, and Michelle A. Josephson

^* Department of Immunology, The Scripps Research Institute, La Jolla, California; and Section of Nephrology, Department of Medicine, University of Chicago, Chicago, Illinois

Correspondence: Dr. Dianne B. McKay, Department of Immunology, IMM-1, The Scripps Research Institute, 10550 North Torrey Pines Road, La Jolla, CA 92037. Phone: 858-784-9716; Fax: 858-784-8069; E-mail: dmckay{at}scripps.edu

Reproductive success is a common, expected outcome for male and female recipients of solid-organ transplants. Men can father children, and women can become pregnant and carry the fetus to delivery. There are, however, important maternal and fetal complications that need to be considered to provide optimal care to the mother and her infant. Although pregnancy is common after the transplantation of all solid organs, guidelines for optimal counseling and clinical management are limited. This review discusses information to help the physician counsel the kidney transplant recipient about risks of pregnancy for the mother and the fetus and provides information to help guide treatment of the pregnant transplant recipient.