HOME HELP FEEDBACK SUBSCRIPTIONS ARCHIVE SEARCH TABLE OF CONTENTS		QUICK SEARCH:   [advanced] Author: Keyword(s): Year:  Vol:  Page:

This Article Full Text Full Text (PDF) All Versions of this Article: CJN.02450508v1 3/6/1861    most recent Alert me when this article is cited Alert me if a correction is posted Citation Map Services Email this article to a friend Similar articles in this journal Similar articles in PubMed Alert me to new issues of the journal Download to citation manager Citing Articles Citing Articles via Google Scholar Google Scholar Articles by Gennari, F. J. Articles by Weise, W. J. Search for Related Content PubMed PubMed Citation Articles by Gennari, F. J. Articles by Weise, W. J.

Acid-Base Disturbances in Gastrointestinal Disease

Department of Medicine, University of Vermont College of Medicine, Burlington, Vermont

Correspondence: Dr. F. John Gennari, 2319 Rehab, UHC Campus, Fletcher Allen Health Care, Burlington, VT 05401. Phone: 802-847-2534; Fax: 802-847-8736; E-mail: fgennari{at}uvm.edu

Disruption of normal gastrointestinal function as a result of infection, hereditary or acquired diseases, or complications of surgical procedures uncovers its important role in acid-base homeostasis. Metabolic acidosis or alkalosis may occur, depending on the nature and volume of the unregulated losses that occur. Investigation into the specific pathophysiology of gastrointestinal disorders has provided important new insights into the normal physiology of ion transport along the gut and has also provided new avenues for treatment. This review provides a brief overview of normal ion transport along the gut and then discusses the pathophysiology and treatment of the metabolic acid-base disorders that occur when normal gut function is disrupted.