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Peripheral Arterial Disease: A Guide for Nephrologists

Stephanie S. DeLoach^*, and Emile R. Mohler, III

^* Department of Medicine, Renal, Electrolyte and Hypertension Division; and Cardiovascular Disease Division, Vascular Medicine Section, University of Pennsylvania, Philadelphia, Pennsylvania

Correspondence: Dr. Emile R. Mohler, III, Hospital of the University of Pennsylvania, 4th Floor Penn Tower Building 3400 Spruce Street, Philadelphia, PA 19104. Phone: 215-662-3275; Fax: 215-662-3255; mohlere{at}uphs.upenn.edu

Cardiovascular disease is a major source of morbidity and mortality for patients with chronic kidney disease (CKD). Peripheral arterial disease (PAD) is a strong predictor of coronary artery disease and a risk factor for mortality in the general population. This is of particular interest to nephrologists because the risk for PAD is increased in CKD. Often, PAD is overlooked as a source of morbidity and as a cardiovascular risk factor in this population. This review serves as an overview of the epidemiology, screening, diagnosis, and treatment of PAD with an emphasis on CKD.